The 2001 rom-com Serendipity follows Jonathan (John Cusack) and Sara (Kate Beckinsale), two strangers who share an immediate romantic connection after a chance encounter. Both involved with other people, they decide to go their separate ways. However, over the course of a few years (and a few serious relationships), fate continues to bring the two together. In order to reunite, the pair must follow the signs . . . and their hearts.